This paper studies the supply-side effect of monetary policy in a multisector economy with input-output linkages. We derive a tractable sufficient statistic for the supply-side effect. The optimal monetary policy leads to an inflation bias due to both initial markups and the supply side effect, and stabilizes a price index by assigning greater weights to (i) larger industries, (ii) industries with stickier prices, and (iii) industries with lower initial markups. In a calibrated model, monetary policy has a strong impact on the supply side of the economy. Without production networks, the supply-side effect of monetary policy declines substantially.